If you are using MSDE for the Helm system database, it can be backed up using the backup tool which is available for download here at:

http://www.webhostautomation.com/members/download_redirect.aspx?id=19

You can use other methods such as IIS Metabase backup to backup IIS and other data, and for domains you can use a simple copy/ftp backup process using MS Backup/Veritas or whatever you use to do backups normally.

—Alex